| Summary of Clinical Studies on Key Ingredients of Cellasis™:
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Palmitoyl Pentapeptide – 4, (Matrixyl™, 5%), containing Micro- Collagen™, (a synthetic
miniature fragment of collagen that is cited to initiate stimulation of collagen synthesis). Clinically
demonstrated to:
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A. |
Stimulate the fibroblasts to synthesize collagen I, and VI, fibrectin, and
glycosaminoglycans (GAG’s) both in vitro and ex-vivo studies. |
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B. |
Increase skin density and thickness. |
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C. |
Decrease wrinkle depth density and volume. |
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D. |
Exceeds retinol results without the negatives ( pro-inflammatory reactions,
thinning of the skin-destructive effect on skin barrier, sensitivities). |
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E. |
Exceeds results of Vitamin C (skin density, volume and wrinkle reduction) |
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F. |
In a study comparing it to TGFB1 (Transformation Growth Factor) and Vitamin C,
Matrixyl produced 217 percent rate of collagen synthesis TBFG1 produced 133 percent and Vitamin C a 142 percent
rate of growth. |
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Nuteline® -The Cellular Biostimulator –A KGF Keratinocytes Growth
Factor (Hazel seed extract, a low molecule weight peptide obtained biotechnologically using a controlled
enzymatic hydrolysis process to stimulate growth of the keratinocytes and the fibroblasts).
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A. |
Stimulates growth of keratinocytes and fibroblasts |
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B. |
Stimulates collagen neo-synthesis. |
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C. |
Speeds epidermal regeneration and augments facial volume, filling creases, lifting
sagging skin and plumping lines. |
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D. |
Protects the elastin against degradation by elastases (enzymes that break down the
elastin). |
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E. |
Remodels skin and restores its barrier function. |
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F. |
Stimulates cell cohesion. |
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Phytokine® - The Cutaneous Firmness Restoring Agent –
(biotechnologically modified Soy Protein) . It restructures the dermis, specifically reactivates neo synthesis of
elastin, GAG’s, collagen, the essential components in dermis that support the cutanous tissue. It offers a
reduction of the collagen III/collagen I ratio.
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“Ex vivo” 3D Clinical studies demonstrated that Phytokine: |
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A. |
Stimulated synthesis of the GAG’s (GlycosAminoGlycans) of aged skin by 66%. |
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B. |
Promoted fibroblastic collagen formation by 65% |
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C. |
Promoted Hyaluronic Acid formation by 74%. Helping to reconstruct the cutaneous
tissue , restoring hydration and improving elasticity and firming of the skin. |
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D. |
Causes neo-synthesis of dermic components involved in maintenance of cutaneous
hydration of the skin. |
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Oligopeptide -20 (Pepha ®-Timp) (Human Tissue Inhibitor of
Matrix Metalloproteinases (MMP’s) It contains a biotechnologically produced human identical tissue inhibitor of
the MMP’s.
In vitro and ex- vivo tests demonstrated that :
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A. |
It protects collagen by inhibiting the metalloproteinases (the enzyme responsible
for collagen breakdown Matrix Metalloproteinase-1 -or Interstitial Colleganese-1) from breaking down collagen |
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B. |
Protects the skin against the degenerative effects of sun induced photo aging. |
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Ameliox – A Liposomal complex of Carnisone (di-peptide) and
Silymarin prevent the cross linking and stiffening of collagen that is caused by glycation and protects the skin
against oxidative stress. Dermatological test results showed: |
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A. |
Immediate smoothing effect |
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B. |
Reduction of frown lines |
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C. |
Improvement in skin firmness |
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D. |
Visible reduction of lines and wrinkles |
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E. |
Slows development of new wrinkles |
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Malachite Extract – derived from the semi precious stone |
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A. |
Fortifies the skin |
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B. |
Protects skin cells against pollution and hostile environment |
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| Complete clinical studies of the above ingredients are available upon request. |
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